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In accordance with the statutes of the institute a research and development committee has been formed, comprising of employees and specialists, who meet four times a year and advise management on directions the institute should be taking in terms of new methods and technology to adopt.
Director of the Institute starts the first board-meeting. The chairman and a vice-chairman will be selected by the board-members. The committee makes decision casts by voting. There are 20 councillors participating in the committee.
The chairman of the research and development committee is the institute’s Deputy Director of Development Marika Väli (telephone +372 663 6603 or e-mail [email protected]
Research articles of EFSI experts over the years:
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Articles 2009 |
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Varvas, Külliki; Kurg, Reet; Hansen, Kristella; Järving, Reet; Järving, Ivar; Valmsen, Karin; Lõhelaid, Helike; Samel, Nigulas (2009). Direct evidence of the cyclooxygenase pathway of prostaglandin synthesis in arthropods: Genetic and biochemical characterization of two crustacean cyclooxygenases. Must, A.; Kõks, S.; Vasar, E.; Tasa, G.; Lang, A.; Maron, E.; Väli, M (2009). Common Variations in 4p Locus are Related to Male Completed Suicide. Anne Must, Gunnar Tasa, Aavo Lang, Eero Vasar, Sulev Kõks, Eduard Maron, Marika Väli (2009). Variation in tryptophan hydroxylase-2 gene is not associated to male completed suicide in Estonian population. Avi R, Huik K, Sadam M, Karki T, Krispin T, Ainsalu K, Paap P, Schmidt J, Nikitina N, Lutsar I. (2009). Absence of genotypic drug resistance and presence of several naturally occurring polymorphisms of human immunodeficiency virus-1 CRF06 cpx in treatment-naive patients in Estonia. |
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Articles 2010 |
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Huik K, Sadam M, Karki T, Avi R, Krispin T, Paap P, Rüütel K, Uusküla A, Talu A, Abel-Ollo K, Lutsar I (2010). CCL3L1 copy number is a strong genetic determinant of HIV seropositivity in Caucasian intravenous drug users. Avi R, Huik K, Sadam M, Karki T, Krispin T, Ainsalu K, Paap P, Schmidt J, Nikitina N, Lutsar I (2010). Characterization of integrase region polymorphisms in HIV type 1 CRF06_cpx viruses in treatment-naive patients in Estonia. Tõnisson, M.; Tillmann, V.; Kuudeberg, A.; Väli, M. (2010). Plasma glucose, lactate, sodium and potassium levels in children hospitalised with acute alcohol intoxication. Lang, K., Pärna, K., Grjibovski, A.M., Väli, M. (2010). Deaths of infants subject to forensic autopsy in Estonia from 2001 to 2005: what can we learn from additional information? Malin von Otter, Sara Landgren, Staffan Nilssonc, Madeleine Zetterberg, Dragana Celojevic, Petra Bergstrome, Lennart Minthon, Nenad Bogdanovic, Niels Andreasen, Deborah R. Gustafson, Ingmar Skoog, Anders Wallin, Gunnar Tasa, Kaj Blennow, Michael Nilsson, Ola Hammarsten, Henrik Zetterberg. Nrf2-encoding NFE2L2 haplotypes influence disease progression but not risk in Alzheimer's disease and age-related cataract. |
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Articles 2011 |
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Töro, Klara; Szilvia, Feher; György, Dunay; Pauliukevicius, Alvydas; Caplinskiene, Marija; Raudys, Romas; Lepik, Delia;Tuusov, Jana; Väli, Marika (2011). Fatal traffic injuries among children and adolescents in three cities (Capital Budapest, Vilnius and Tallinn). Tõnisson, Mailis; Tillmann, Vallo; Kuudeberg, Anne; Väli, Marika (2011). Plasma cortisol, testosterone, estradiol and progesterone levels in children with acute alcohol intoxication. Rudolph T, Sjölander A, Palmér MS, Minthon L, Wallin A, Andreasen N, Tasa G, Juronen E, Blennow K, Zetterberg H, Zetterberg M (2011). Ubiquitin carboxyl-terminal esterase L1 (UCHL1) S18Y polymorphism in patients with cataracts. |
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Articles 2012 |
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Tuusov, Jana; Vals, Kaire; Tõnisson, Mailis; Riikoja, Aime; Denissov, Gleb; Väli, Marika (2012). Fatal poisoning in Estonia 2000-2009. Trends in illegal drug-related deaths. Ringmets, I.; Tuusov, J.; Lang, K.; Väli, M.; Pärna, K.; Tõnisson, M.; Helander, A.; McKee, M.; Leon, DA (2012). Alcohol and premature death in Estonian men: a study of forensic autopsies using novel biomarkers and proxy informants. Denissov, Gleb; Tuusov, Jana; Tõnisson, Mailis; Lepik, Delia; Väli, Marika (2012). The impact of changing classification of official fatal poisoning figures. Järving, Reet; Lõokene, Aivar; Kurg, Reet; Siimon, Liina; Järving, Ivar; Samel, Nigulas (2012). Activation of 11R-Lipoxygenase Is Fully Ca2+-Dependent and Controlled by the Phospholipid Composition of the Target Membrane. Kukk, Kaia; Järving, Reet; Samel, Nigulas (2012). Purification and characterization of the recombinant human prostaglandin H synthase-2 expressed in Pichia pastoris. Eek, Priit; Järving, Reet; Järving, Ivar; Gilbert, Nathaniel C.; Newcomer, Marcia E.; Samel, Nigulas (2012). Structure of a Calcium-dependent 11R-Lipoxygenase Suggests a Mechanism for Ca2+ Regulation. |
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Articles 2013 |
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Celojevic D, Nilsson S, Behndig A, Tasa G, Juronen E, Karlsson JO, Zetterberg H, Petersen A, Zetterberg M (2013). Superoxide dismutase gene polymorphisms in patients with age-related cataract. Mailis Tõnisson, Vallo Tillmann, Anne Kuudeberg, Delia Lepik and Marika Väli (2013). Acute Alcohol Intoxication Characteristics in Children. S. Remmer, A. Kuudeberg, M. Tõnisson, D. Lepik, M. Väli (2013). Cardiac troponin T in forensic autopsy cases. Huik K, Avi R, Carrillo A, Harper N, Pauskar M, Sadam M, Karki T, Krispin T, Kongo UK, Jermilova T, Rüütel K, Talu A, Abel-Ollo K, Uusküla A, Ahuja SK, He W, Lutsar I (2013). CCR5 haplotypes influence HCV serostatus in Caucasian intravenous drug users. |
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Articles 2014 |
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Jana Tuusov, Katrin Lang, Marika Väli, Kersti Pärna, Mailis Tõnisson, Inge Ringmets, Martin McKee, Anders Helander, David A Leon (2014). Prevalence of alcohol-related pathologies at autopsy: Estonian Forensic Study of Alcohol and Premature Death. Celojevic D, Nilsson S, Kalaboukhova L, Tasa G, Juronen E, Sjölander A, Zetterberg H, Zetterberg M (2014). Genetic variation of superoxide dismutases in patients with primary open-angle glaucoma. |
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Articles 2015 |
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Sadam M, Tasa G, Tiidla A, Lang A, Axelsson EP, Pajnič IZ (2015). Population data for 22 autosomal STR loci from Estonia. P. Mangin, F. Bonbled, M. Väli, A. Luna, T. Bajanowski, H. P. Hougen, B. Ludes,D. Ferrara D. Cusack, E. Keller, N. Vieira (2015). European Council of Legal Medicine (ECLM) accreditation of forensic pathology services in Europe. Boglárka Marcsa, Krisztina Vörös, Aletta Váradi-T, Marika Väli, Péter Sótonyi, Katalin Kovács, Klára Törő (2015). Distribution Of Environmental-Related Death Cases Across Europe- Environmental Accidents. Dragana Škiljić, Staffan Nilsson, Mona Seibt Palmér, Gunnar Tasa, Erkki Juronen, Anders Behndig, Jan-Olof Karlsson, Anne Petersen, Henrik Zetterberg & Madeleine Zetterberg (2015). Estrogen-related Polymorphisms in Estonian Patients with Age-related Cataract. Sabre, Liis; Remmer, Sünne; Adams, Anu; Väli, Marika; Rekand, Tiina; Asser, Toomas; Kõrv, Janika (2015). Impact of fatal cases on the epidemiology of traumatic spinal cord injury in Estonia. |
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Articles 2016 |
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D. Cusack, S. D. Ferrara, E. Keller, B. Ludes, P. Mangi, M. Väli, N. Vieira (2017). European Council of Legal Medicine (ECLM) principles for on-site forensic and medico-legal scene and corpse investigation. Celojevic D, Abramsson A, Seibt Palmér M, Tasa G, Juronen E, Zetterberg H, Zetterberg M (2016). EPHA2 polymorphisms in Estonian patients with age-related cataract. |
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Articles 2017 |
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Saar S, Lomp A, Laos J, Mihnovitš V, Šalkauskas R, Lustenberger T, Väli M, Lepner U, Talving P. Population-Based Autopsy Study of Traumatic Fatalities (2017). |
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Articles 2018 |
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Karis, Karina, Eskla, Kattri-Liis, Kaare, Maria, Taht, Karin, Tuusov, Jana, Visnapuu, Tanel, Innos, Jurgen, Jayaram, Mohan, Timmusk, Tonis, Weickert, Cynthia S, Väli, Marika, Vasar, Eero, Philips, Mari-Anne (2018). Altered Expression Profile of IgLON Family of Neural Cell Adhesion Molecules in the Dorsolateral Prefrontal Cortex of Schizophrenic Patients. Lepik,Delia; Tõnisson, Mailis; Kuudeberg, Anne; Väli, Marika (2018). Glycated haemoglobin (HbA1c) for post-mortem diagnosis of diabetes. |
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Articles 2019 |
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Urb M, Anier K, Matsalu T, Aonurm-Helm A, Tasa G, Koppel I, Zharkovsky A, Timmusk T, Kalda A (2019). Glucocorticoid Receptor Stimulation Resulting from Early Life Stress Affects Expression of DNA Methyltransferases in Rat Prefrontal Cortex. Keller E, Santos C, Cusack D, Väli M, Ferrara D, Ludes B; Mangin P, Payne-James J.J, Viera D (2019). European council of legal medicine (ECLM) guidlines for the examination of suspected elder abuse (2019). |
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Articles 2020 |
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Tõnisson M, Lepik D, Kuudeberg A, Riikoja A, Barndõk T and Väli M. Relationship between Blood Ethanol Concentration, Ethyl Glucuronide and Ethyl Sulfate and Clinical Signs of Alcohol Intoxication (2020). Ester Oras, Jaanika Anderson, Mari Tõrv, Signe Vahur, Riina Rammo, Sünne Remmer, Maarja Mölder, Martin Malve, Lehti Saag, Ragnar Saage, Anu Teearu-Ojaka, Pilleriin Peets, Kristiina Tambets, Mait Metspalu, David C. Lees, Maxwell V. L. Barclay, Martin J. R. HallISalima Ikram, Dario Piombino-Mascali. Multidisciplinary investigation of two Egyptian child mummies curated at the University of Tartu Art Museum, Estonia (Late/Graeco- Roman Periods). Sünne Remmer, Delia Lepik, Mailis Tõnisson, Anne Kuudeberg, MarikaVäli Alcohol, Cardiovascular Death and Postmortem Lipids (Total Cholesterol, HDL, Apo A1 And Apo B), A Case-Control Study (2020). |
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Articles 2021 |
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Jelena Mõttus, Siim Maiste, Priit Eek, Erkki Truve, Cecilia Sarmiento Andreas-Christian Hade 1,2, Mari-Anne Philips 3,4,*, Ene Reimann 5, Toomas Jagomäe 3,4, Kattri-Liis Eskla 3,4, Tanel Traks 6, Ele Prans 7, Sulev Kõks 8,9, Eero Vasar 3,4 and Marika Väli 1,2. Chronic Alcohol Use Induces Molecular Genetic Changes in the Dorsomedial Thalamus of People with Alcohol-Related Disorders Anu Aaspõllu 1,*, Raili Allmäe 2, Fred Puss 3,4, Walther Parson 5,6, Küllike Pihkva 7, Kairi Kriiska-Maiväli 8 and Arnold Unt 9 The Unique Identification of an Unknown Soldier from the Estonian War of Independence |
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Articles 2022 |
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R. Cecchi 1,2, D. Cusack 3,4, B. Ludes 3,5, B. Madea 3,6, D. N. Vieira 3,7, E. Keller 3,8, J. Payne‑James 3,9, A. Sajantila 3,10, M. Vali 3, 11, R. Zoia 3,12, N. Cucurachi 1,2, M. L. Schirripa 1,2, F. Marezza 1,2, L. Anzillotti 1,2, L. Donato 1,2, C. Cattaneo 3, 12, D. Favretto 13,14, S. Pelotti 13,15, V. Pinchi 13,16, S. Vanin 13,17, M. Gherardi 1,18 European Council of Legal Medicine (ECLM) on‑site inspection forms for forensic pathology, anthropology, odontology, genetics, entomology and toxicology for forensic and medico‑legal scene and corpse investigation: the Parma form |
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Articles 2023 |
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Sten Saar, Edgar Lipping, Artjom Bahhir, Maarja Talviste, Jaak Lepp, Marika Väli, Peep Talving „ Outcomes of resuscitative and emergent thoracotomies following injury at the largest trauma center in Estonia“. European Journal of Trauma and Emergency Surgery (2023) |